Valenzuela Lab
 
Cpicta
NV

Dr. Nicole Valenzuela Department of Ecology, Evolution, and Organismal Biology

Iowa State University

251 Bessey Hall. Ames, IA 50011

(515) 294-1285

nvalenzu@iastate.edu

NSF

RESEARCH OVERVIEW We are interested in studying how ecology affects the structure, function, and evolution of the genome and its role in the development and evolution of complex phenotypes. This helps us understand the evolution of biological diversity and how it responds to environmental change.

 

 
 

News And Events Our latest pubs and more

CONSERVATION: Extreme thermal fluctuations from climate change unexpectedly accelerate demographic collapse of vertebrates with temperature-dependent sex determination. Scientific Reports 2019. PDF

SEX CHROMOSOME EVOLUTION: Discovery of putative XX/XY male heterogamety in Emydura subglobosa turtles exposes a novel trajectory of sex chromosome evolution in Emydura. Cytogenetic and Genome Research. 2019. In Press.

EPIGENETICS: Thermal response of epigenetic genes informs turtle sex determination with and without sex chromosomes Sexual Development 2018. PDF

PHYLOGENOMICS: Reconstruction of genome organization in the diapsid common ancestor permits tracing of chromosome evolution in avian and non-avian dinosaurs. Nature Communications 2018. PDF

PHYLOGENOMICS: Chromosomal rearrangements during turtle evolution altered the synteny of genes involved in vertebrate sex determination. Cytogenetic and Genome Research 2018 - In press.

MOLECULAR EVOLUTION: Putative independent evolutionary reversals from genotypic to temperature-dependent sex determination are associated with accelerated evolution of sex-determining genes in turtles. Journal of Molecular Evolution. 2018. PDF

GRADUATE AND POSTDOCTORAL POSITIONS Positions are available for individuals interested in evolutionary biology, sex determination, evo-devo, chromosome and genome evolution, or climate change. Click here for details.

Sex Determination Evolution and Regulation of Developmental Networks

Embryos

Why do organisms vary so remarkably in the ways they produce males and females? Our work focuses on comparative evolutionary and ecological genomics related to the evolution of developmental pathways, particularly those that underlie the development of the sexual phenotype.

Phylogenomics Sex Chromosomes and Genome Organization

Chromosomes

What are the causes and consequences of chromosome evolution? We are studying (a) the evolution of sex chromosomes and the genes they contain, plus (b) the genome rearrangements responsible for changes in diploid number across turtles and their association with transitions in sex determination.

Links

ITA
TSDbook
EEOB
ISU
 
treeofsex
Tree of Sex Database Paper
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